The SARS-CoV-2 virus, like many other viruses, is bad news for the brain. Spike proteins alone can cause brain fog. Because the spike protein enters the brain, the virus is also likely to reach the brain.
There is ample evidence that people with Quid 19 develop cognitive impairments such as cerebral palsy and extreme fatigue, and researchers are discovering the cause. In a study published December 16 in the journal Nature Neuroscience, researchers found that the spike protein in mice crosses the blood-brain barrier. This study shows that the Covid 19 virus, SARS-CoV-2, can enter the brain.
The spike protein, often called the S1 protein, determines which cells a virus can enter. William Banks“Viruses usually do what their binding proteins do,” said a professor of medicine at the University of Washington School of Medicine and one of the study’s authors. Banks believes that binding proteins, such as S1, usually cause damage on their own by detaching from the virus and causing inflammation. “S1 protein probably produces cytokines and inflammatory products in the brain,” he says.
In scientific circles, severe inflammation caused by Covid 19 infection is called “cytokine storm.” The immune system overreacts as soon as it sees the virus and its proteins trying to kill the invading virus. Eventually, the infected person becomes overwhelmed with fatigue and cognitive problems.
Banks and his team observed the reaction in HIV and wanted to see if the same thing happened with SARS CoV-2. Banks says the S1 protein in SARS-CoV2 virus and the gp120 protein in HIV-1 infection have similar functions. They are glycoproteins that are prominent features of proteins that bind to other receptors. Glycoproteins are proteins that have a lot of sugars on their surface. These proteins act like clusters of viruses and attach to other receptors. Both cross the blood-brain barrier, and S1, like gp120, is probably toxic to brain tissue.
Banks has done a lot of research on HIV-1 and the gp120 protein and the blood-brain barrier. “It was like acquaintance,” he says. Banks Laboratory is studying the blood-brain barrier in Alzheimer’s, obesity, diabetes and HIV; But they stopped their research, and in April, all 15 people in the lab began testing the S1 protein. The new study could explain many of the side effects of Covid 19. Banks says:
We know that when you have a cavity infection, you have trouble breathing because of an infection in your lungs; But another explanation is that the virus enters the respiratory centers of the brain and causes such problems.
Jacob Raber, In their experiments, said that in their experiments, the transmission of S1 in the olfactory bulb and all male mice was faster than that of female mice. This observation may be related to the increased sensitivity of men to more severe cases of Covid 19. Banks has a message for people who do not take the virus seriously:
You do not want to be infected with this virus. Many of the effects of the Covid virus can be exacerbated or sustained by the virus entering the brain, and those effects may persist for a long time.